Ayahuasca Manifesto

Our priority is your safety and well-being, and to guide you to personal healing, growth and spiritual connection. Please be as forthcoming and detailed as possible when answering the questions. If any potential medical contraindications are present, we will inquire further to ensure your safety. By registering, you are declaring that you are in physical and mental condition appropriate to the activities described. We will provide the most secure environment to work with medicinal plants as much as possible and ensure your welfare to the best of our abilities, at all times. In return, we ask that you behave responsibly and do not endanger yourself or others. 

Although plant medicines have not been found to cause psychosis or other psychiatric disturbances, it can be dangerous to those with a history of psychological conditions. Please inform us of any history of mental health conditions in the past. 

It is essential to stop taking the substances listed in this document and give your system sufficient time to remove them from the body prior to ceremony. We will provide advice on how to proceed during your booking process. Please consult your doctor if you are in any doubt. You should not stop taking prescribed medications without consulting your doctor. 

If you are taking any drugs or herbs it is important to review the information carefully below. For your safety, all drugs and herbs listed below should be discontinued in a safe manner. Please consult your physician before changing your medical schedule.

Herbal Contraindications for some of our medicinal plants:

St. Johns Wort • Kava • Kratom • Ephedra • Ginseng • Yohimbe • Sinicuichi • Rhodiola Rosea • Kanna • Boswellia • Nutmeg • Scotch Broom • Licorice Root • Sassafras 

Cannabis Interactions: Smoking marijuana in combination with other plant medicines may distort, darken and/or confuse the overall experience, acting as a blockage. Given the general amplified sensitivity of all participants during the event, marijuana negatively affects not just the person who used it, but potentially other participants’ experiences as well as the overall energy of the medicine circle. It is important that your system is clear of cannabis at least 3-4 weeks prior to ceremony.

Contraindications: Drugs and Medications 

1. Any medication that contains MAO inhibitors (MAO-Is) are known to cause      dangerous side effects when taken in conjunction with consuming some medicinal plants and should be suspended.
2. Any medication that has an effect on the serotonin system, including Selective      Serotonin Reuptake Inhibitors (SSRIs), can induce serotonin syndrome, with      potentially fatal results when combined with some medicinal plants. We advise that SSRI medications be suspended SIX WEEKS prior to taking medicinal plants to allow the system to clear in time.
3. Some of these drugs may cause side effects when you stop taking them so you should allow plenty of time for these to subside and always consult your      physician before changing your medical schedule.

List of Contraindicated Drugs (3, 5): *this is not a comprehensive list.

• Other MAO-Is • SSRI’s (any selective serotonin reuptake inhibitors) • Asthma inhalers • Antihypertensives (high blood pressure medicine) • Appetite suppressants (diet pills) • Medications for asthma, bronchitis, or other breathing problems • Antihistamines, medicines for colds, sinus problems, hay fever, or allergies (any cold, cough, or flu preparations, and any drug with DM, DX or -tuss in its name.) • CNS (central nervous system) depressants • Antipsychotics • Barbiturates • Tranquilizers • Sympathomimetic amines (including pseudo ephedrine and ephedrine) • Alcohol • Amphetamines • Opiates • Mescaline (any phenethylamine) • Barbiturates 4 of 9 Specific Contraindicated Drugs (3, 5): • Actifed • Adderall • Alaproclate • Albuterol (Proventil, Ventolin) • Amantadine hydrochloride (Symmetrel) • Amineptine • Amitriptaline • Amoxapine (Asendin) • Asarone/Calamus • Atomoxedine • Befloxetone • Benadryl • Benylin • Benzedrine • Benzphetamine (Didrex) • Bicifadine • Brasofensine • Brofaromine • Bromarest-DM or -DX • Bupropion (Wellbutrin) • Buspirone (BuSpar) • Butriptyline • Carbamazepine (Tegretol, Epitol) • Chlorpheniramine • Chlor Trimeton • Cimoxetone • Citalopram • Clomipramine (Anafranil) • Cocaine • Codeine • Compoz • Cyclobenzaprine (Flexeril) • Cyclizine (Marezine) • Dapoxotine • Desipramine (Pertofrane, Norpramin) • Desvenlafaxine • Dextroamphetamine (Dexedrine) • Dextromethorphan (DXM) • Dibenzepin • Dienolide kavapyrone desmethoxyyangonin • Diethylpropion • Dimetane-DX • Disopyramide (Norpace) • Disulfiram (Antabuse) • Dopamine (Intropin) 5 of 9 • Dosulepin • Doxepin (Sinequan) • Dristan Cold & Flu • Duloxetine • Emsam • Ephedrine • Epinephrine (Adrenalin) • Escitalopram • Femoxitine • Fenfluramine (Pondimin) • Flavoxate Hydrochloride (Urispas) • Fluoxetine (Prozac) • Fluvoxamine • Furazolidone (Furoxone) • Guanethedine • Guanadrel (Hylorel) • Guanethidine (Ismelin) • Hydralazine (Apresoline) • 5 Hydroxytryptophan • Imipramine (Tofranil) • Iprindole • Iproniazid (Marsilid, Iprozid, Ipronid, Rivivol, Propilniazida) • Iproclozide • Isocarboxazid (Marplan) • Isoniazid (Laniazid, Nydrazid) • Isoniazid rifampin (Rifamate, Rimactane) • Isoproterenol (Isuprel) • L dopa (Sinemet) • Levodopa (Dopar, Larodopa • Linezolid (Zyvox, Zyvoxid) • Lithium (Eskalith) • Lofepramine • Loratadine (Claritin) • Macromerine • Maprotiline (Ludiomil) • MDA • MDEA • MDMA (Ecstasy) • Medifoxamine • Melitracen • Meperidine (Demerol) • Metaproterenol (Alupent, Metaprel) • Metaraminol (Aramine) • Methamphetamine (Desoxyn) • Methyldopa (Aidomet) • Methylphenidate (Ritalin) 6 of 9 • Mianserin • Milnacipran • Minaprine • Mirtazapine (Remeron) • Moclobemide • Montelukast (Singulair) • Nefazodone • Nialamide • Nisoxetine • Nomifensine • Norepinephrine (Levophed) • Nortriptyline (Aventyl) • Oxybutynin chloride (Ditropan) • Oxymetazoline (Afrin) • Orphenadrine (Norflex) • Pargyline (Eutonyl) • Parnate • Paroxetine (Paxil) • Pemoline (Cylert) • Percocet • Pethedine (Demerol) • Phendimetrazine (Plegiline) • Phenelanine • Phenergen • Phenmetrazine • Phentermine • Phenylephrine (Dimetane, Dristan decongestant, Neo Synephrine) • Phenylpropanolamine (in many cold medicines) • Phenelzine (Nardil) • PMA • Procarbazine (Matulane) • Procainamide (Pronestyl) • Protriptyline (Vivactil) • Pseudoephedrine • Oxymetazoline (Afrin) • Quinidine (Quinidex) • Rasagiline (Azilect) • Reboxetine • Reserpine (Serpasil) • Risperidone • Robitussin • Salbutemol • Salmeterol • Selegiline (Eldepryl) • Sertraline (Zoloft) • Sibutramine 7 of 9 • Sumatriptan (Imitrex) • Terfenadine (Seldane D) • Tegretol • Temaril • Tesofensine • Theophylline (Theo Dur) • Tianeptine • Toloxatone • Tramidol • Tranylcypromine (Parnate) • Trazodone • Tricyclic antidepressants (Amitriptyline, Elavil) • Trimipramine (Surmontil) • Triptans • Tryptophan • Tyrosine • Vanoxerine • Venlafaxine (Effexor) • Viloxezine • Vicks Formula 44-D • Yohimbine • Zimelidine • Ziprasidone (Geodon) • 

Potential complications that can occur while taking these listed drugs in conjunction with some medicinal plants:

• Using stimulants with MAO-Is is particularly dangerous and can be potentially      fatal. 
• Using cocaine, amphetamines or MDMA (Ecstasy) with MAO-Is may cause a severe      increase in blood pressure, increasing the chances for stroke and cerebral      hemorrhage and making it possible to overdose on a relatively small amount of cocaine. (A fatality has been recorded involving combining Peganum harmala and cocaine. Fatalities resulting from combining amphetamines with pharmaceutical MAO-Is are recorded in medical literature.) 
• Using other serotonin agonists or precursors with an MAO-I can lead to serotonin      syndrome. The main symptom of serotonin symptom may be a severe and long-lasting headache (the same symptom as MAO-I tryptamine interaction) and/or fever (as high as 40 °C / 104 °F or more) Other symptoms of serotonin syndrome may include rapid heartbeat, shivering, sweating, dilated pupils, intermittent tremor or twitching, overactive or over-responsive reflexes, hyperactive bowel sounds, high blood pressure. Severe serotonin syndrome may lead to shock, agitated delirium, muscular rigidity and high muscular tension. renal failure, seizures, and can be      life-threatening. 
• Using Tricyclic antidepressants within two weeks of taking MAO-Is may cause      serious side effects including sudden fever, extremely high blood pressure, convulsions, and death. 
• Using Fluoxetine (Prozac) within five weeks of taking MAO-Is may cause high      fever, rigidity, high blood pressure, mental changes, confusion and hypomania. 
• Using Benzedrine, Benzphetamine, Desipramine, Desoxyn, Dexedrine, Dopamine,      Ephedrine (contained in Marax, Quadrinal, and other asthma drugs),      Epinephrine, 8 of 9 Guanadrel, Guanethidine, Hydralazine, Isoproterenol, L-dopa, Metaraminol, Methyldopa, Mirtazamine, Norepinephrine Oxymetazoline,      Phendimetrazine, Phentermine, Phenylephrine, Phenylpropanolamine,      Pseudoephedrine, Ritalin, or Venlafaxine with MAO-Is may cause a hypertensive crisis (severe spike in blood pressure). 
• Using Adderall with MAO-Is can result in high body temperature, seizure, and in      some cases coma. 
• Using Bupropion (Wellbutrin) within five weeks of taking MAO-Is may cause serious      side effects such as seizures. 
• Using Buspirone (Buspar) with MAO-Is may cause high blood pressure and increased      sedative effects. 
• Using Carbamazepine (Tegretol) with MAO-Is may result in fever and may increase      seizures, especially in epileptics. •
• Using Clomipramine with MAO-Is may cause high fever (hyperpyrexic crisis) and      seizures. 
• Using CNS depressants with MAO-Is may increase the depressant effects. 
• Using Desipramine (Norpramin, Pertofrane) with MAO-Is may result in hypertensive      crisis. 
• Using Dextromethorphan with MAO-Is may cause excitement, high blood pressure,      and fever, or brief episodes of psychosis. 
• Using Fenfluramine with MAO-Is may result in fever (hyperpyrexic crisis). 
• Using Lithium with MAO-Is may cause fever and serotonin syndrome. 
• Using Meperidine (Demerol) with pharmaceutical MAO-Is has resulted in deaths      from a single dose. 
• Using Metaproterenol or other beta-adrenergic bronchodilators with MAO-Is may      cause blood pressure elevation and rapid heartbeat. 
• Using Mirtazapine (Remeron) with MAO-Is may result in hypertensive crisis. •      Using Nefazodone (Serzone) may result in high fever. 
• Using Temaril with MAO-Is may increase chance of side effects. 
• Using Terfenadine with MAO-Is may cause an increase in MAO-I blood levels. 
• Using Theophylline with MAO-Is may cause rapid heartbeat and anxiety. 
• Using Trazodone (Desyrel) with MAO-Is may result in high fever. 
• Using Tryptophan or L-tryptophan with MAO-Is may cause disorientation, confusion, amnesia, delirium agitation, memory impairment, hypomanic signs, shivering. 
• Using Venlafaxine (Effexor) with MAO-Is may result in hypertensive crisis. 
• Using Ziprasidone (Geodon) with MAO-Is may cause serotonin syndrome. 
• Using alcohol with MAO-Is may cause side effects like angina (chest pain) or headaches. The headache may mask or be mistaken for hypertensive crisis caused by MAO-I interaction. MAO-Is can also increase the sedative effect of alcohol. 
• Using opiates with MAO-Is carries a risk of respiratory depression. 
• Using diuretics with MAO-Is may cause a greater drop in blood pressure than      normal and increase in MAO-I blood levels. 
• Using anesthetics with MAO-Is may potentiate the anesthetic effect. 
• Using sleeping pills, tranquilizers (major or minor), or barbiturates with MAO-Is may increase the sedative effect. 

References 

1. Hales RE,      Yudolfsky SC, Talbott JA (Editors) (1994). American Psychiatric Press      Textbook of Psychiatry. Washington, D.C.: American Psychiatric Press, Inc.      940-3.
2. McCabe BJ      (1986). Dietary tyramine and other pressor amines in MAO-I regimes: A      review. Journal of The American Dietetic Association. 86:8:1059-64.